| Item | Focus | Criterion | Measures | Technique process | Intellectual property, customer requirement and possibility of commercial scale production | No invasion of intellectual property, and meet with customer’s requirements on process and make it feasible for commercial scale production. | Refer to relative documents from web, inner technique database and get information from customer as much as possible. | | Validity of intermediates and auxiliary materials | Substances under official control, such as CCl4. Raw materials and auxiliary goods easy to bring in dangerous substances. | Fully abide by the stipulation on substances under official control, esp. in the line of pharmaceutical. | Firstly fully communicate with customers, then with the maker on key points and details. | | Yield | Whether or not to reach the general standard of classic reaction. | If the yield is too low, the maker should focus on development of process, instead of cost accounting in advance. | Fully understanding on relative documents, reaction and inspect real situation on process. | | Environment Protection | Main wastes: species, dangerous scope, treatment and effect scope | Production should be in accordance with the demand of local government protection, left no hidden trouble. | Fully understand the wastes caused by the process and confirm one by one with the maker. |
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